Production of nanobodies in Andean camelids and their most common applications: A general review in the medical field.

نویسندگان

چکیده

The heavy chain fraction present in Camelidae antibodies is so-called nanobodies. They have different characteristics when compared to immunoglobulin G, like more diminutive size, higher affinity, shorter half-life serum, etc. These proteins are codified by B lymphocytes cDNAs and can be produced hosts Escherichia Coli, Pichia Pastoris, plant cells even insect cells. Andean camelids been mainly used the region of South America as transport means source raw materials fibers meat, then being great economic importance. However, Ecuador, potential these animals a biomedical products has not investigated or exploited yet. Due scarce information related molecules their industrial production country, this review aims remark on most common medical application nanobodies from camelids; also, applications described. Keywords: Cancer, Coronavirus, VHH, production, treatment, diagnosis.

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ژورنال

عنوان ژورنال: Bionatura (Ibarra - Impresa)

سال: 2023

ISSN: ['1390-9347', '1390-9355']

DOI: https://doi.org/10.21931/rb/2023.08.02.13